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60 The activated sensor protein recruits the adaptor protein, which acts as a scaffold for assembling the inflammasome complex

With regard to the functioning of Mn-SOD, including its involvement in neutralizing free radicals as well as the pathway by which this enzyme is activated, which is under the influence of elevated levels of tumor-necrosis factor-alpha (TNF-), the factor contributing to the maintenance of the inflammatory state in endometriosis, the association between Mn and endometriosis occurs [126]