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Furthermore, the endoplasmic reticulum (ER) is another cellular source for ROS due to alterations in ER-regulated protein folding pathways [13]

Elsevier Saunders, Philadelphia Maenhaut C, Christophe D, Gilbert Vassart MD (2015) Ontogeny, anatomy, metabolism and physiology of the thyroid
Intracellularly, GSH has the prominent role of acting as the redox buffer to protect the proper folding of proteins

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