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Typical scenarios that prevent you from digesting and absorbing nutrients by promoting the fight or flight mode include: Facing physical or emotional threats from others Feeling constantly overwhelmed, frustrated, or out of control Feeling excited about something to the point where it may interfere with your sleep Being over-stimulated by foods (too much sugar, caffeine) Being over-stimulated by drugs (cocaine, LSD, methamphetamines) Being over-stimulated by activities (exercise, watching TV, playing video games) Being stressed Feeling anxious or irritable Feeling angry or agitated Summary of How Your Mood Affects Digestion Fight or Flight Mode: When the sympathetic nervous system takes over, it prioritizes immediate survival needs