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10.1038/s41392-023-01570-w 16 ChenY.BrandizziF
Yamazaki, Y., Zhao, N., Caulfield, T
In an in vivo study comparing the blood glucose levels-lowering effects of saline, PO-free insulin solution, SC insulin solution, uncoated NCs, and pHPMA nanoparticles with the lowest charge density in diabetic rats, pHPMA nanoparticles demonstrated a maximal reduction of 50% in blood glucose levels, at 4 h post-administration with a dosage of 75 IU/kg
