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Figure 3 Figure 4 For both groups equally, total leukocyte counts ( Figure 3A ) showed a constant increase to more than double concentration from d 42 ap until 4 h pp where it reached its maximum

The addition of exogenous melatonin improves the intestinal microbial composition and circadian rhythm in high-fat diet-fed mice, thereby regulating the hosts metabolic circadian clock and lipid metabolism [57]