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The research was funded by the Koch Institute Dana-Farber Bridge Project and the National Institutes of Health.

This could give it broader therapeutic potential for: As of 2025, Dihexa has not yet entered large-scale, double-blind, placebo-controlled clinical trials for widespread human use

Indications and Use: Trazodone HCl is FDA-approved for the treatment of major depressive disorder (MDD) in adults