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Studies such as this one published in PMC highlight the role of malabsorption from mucocutaneous disorders like epidermolysis bullosa can lead to deficiencies that cannot be addressed adequately with oral supplements

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Published online April 2013:AB24

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There is a chance that a small number of people may also experience more serious side effects that include allergic reactions and heart issues

[7] Published experience and post-marketing reports suggest that adverse reactions to topical GHK-Cu are uncommon and, when they occur, tend to be mild and localized