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The novel inhibitor PRI-724 for Wnt/-catenin/CBP signaling ameliorates bleomycin-induced pulmonary fibrosis in mice

This requires considerations for fertility preserving approach

Dynamic light scattering (DLS) on a 90 Plus/BI-MAS instrument (Brookhaven Instruments Corporation, USA) was used to measure the size and zeta potential of nanoprobe at pH 7.4 or 6.5

After centrifugation, the supernatant solution was collected and purified using semi-preparative HPLC, C4 column and gradient of 2060% B to give the desired product in ~45% yield (Supplementary Fig

This binding is crucial because it not only helps in the transport of zinc but also plays a role in maintaining the stability and solubility of zinc in the blood

Biochemistry 46 , 28122822 (2007)