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10.1016/j.peptides.2011.02.011 Peptides 159 TakedaJ.SeinoY.TanakaK.FukumotoH.KayanoT.TakahashiH.et al (1987)

The stability of the analogs is based on their sensitivity to autoxidation, and the moderately stable 7 and 8 degrade slower than curcumin whereas unstable 15 and 16 degrade faster 20

The adrenal glands mainly produce cortisol, aldosterone and adrenaline, which are important hormones that play arole in regulating metabolism, the immune system, blood pressure, our ability to respond to stress and several other important functions(2)

Targeted medicines with few adverse effects may become a reality once these pathways are understood

I don't obsess over her pitting edema to the shins, but I do note the brawny tree-bark appearance of her skin that seems to have developed over a decade