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The activation of the AGE-RAGE axis amplifies chronic inflammation and oxidative stress in both microenvironments, while SNS overactivity and elevated catecholamines induce vasoconstriction in both testicular and penile vasculature, forming a vicious cycle of sympathetic activation and inflammatory damage (207)

Gallego-Durn R, Ampuero J, Maya-Miles D, Pastor-Ramrez H, Montero-Vallejo R, Rivera-Esteban J, et al

Many researchers have reported a connection between CVD phenotypes and changes in the relative abundance of specific microbial taxa or the richness or variety of the bacteria in the gut ( The gut barrier is a complex system that separates the intestinal lumen from the rest of the body (28, 29)

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J), fenugreek seed extract (Trigonella foenum-graecum L.), oat leaf and stem extract (Avena sativa L.), zinc sulfate, fireweed herb extract (Epilobium parviflorum Schreb.), cayenne pepper fruit extract (Capsicum annuum L