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Vitamin B12 injections are commonly given intramuscularly or deep subcutaneously, depending on the product label and clinical direction

doi: 10.1001/jama.289.14.1826

You may want to talk with a doctor about B12 shots if you regularly experience: Persistent fatigue and lethargy Muscle aches and joint pain Loss of appetite Nausea, constipation, diarrhea, or cramping Poor memory or difficulty concentrating Mood swings Can B12 Injections Help With Mood Enhancement and Mental Clarity

Nevertheless, there are recognizable patterns to anticipate

Vitamin B12 deficiencies are more common in vegetarians and vegans since meat, fish, and eggs are the richest sources of vitamin B12

NNMT is increasingly recognized as a regulator of neuronal energy balance and oxidative stress