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The entire vial provides four 2.5 mg doses or two 5 mg doses

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There are several theories regarding underlying mechanisms

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International availability depends on local pharmaceutical regulations and licensing requirements in other countries

While there is not much doubt that traumatic disc herniation can occur in a degenerated segment, 5 and, although documented in biomechanical in-vitro studies, 39 the existence of an isolated annulus fiber rupture with NP herniation caused by a single traumatic event without (proven) pre-existing DD is still debated in the clinical literature