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The resulting mixture was heated at 60 C for 2 h with constant stirring and then allowed to cool to room temperature

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Lysosome-targeted photodynamic therapy PDT uses light-activated photosensitizers to generate lethal ROS within specific subcellular compartments, and lysosomal targeting has increasingly been explored as a means to enhance therapeutic efficacy and modulate immune responses [117]

Careful consideration of the specific types of immune cells that create variability in within- and between-subjects DNA methylation levels remains an important issue within this work