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American Journal of Psychiatry, 169(12), 1267-1274

Zhong Z

Journal of the American College of Nutrition

This persistent pro-inflammatory milieu plays a critical role in promoting adiposity and fostering insulin resistance in the host, as shown in Table 3

doi: 10.1038/s41467021-276425 30 JonesGDDrozBGrevePGottschalkPPoffetDMcGrathSPet al

288 Existing studies have demonstrated that L-DON and JHU-083 can extensively inhibit Gln metabolizing enzymes and activate AMPK and c-Myc to inhibit glycolysis, thereby stopping tumor metabolic activity, alleviating hypoxia, and increasing the concentration of Gln and glucose in TME