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Description
11 The main pathological feature of PD is the buildup of toxic -synuclein, a protein that forms into insoluble fibrils called Lewy bodies
These effects appear to arise indirectly through vascular support, inflammation control, and cellular protection rather than direct neurotransmitter stimulation

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They also degrade quickly when exposed to light and air, losing potency

Annually, it impacts approximately 3% of older people and ranks second behind Alzheimers disease (1)

The analogues were synthesised via Fmoc-solid-phase peptide synthesis, and they were characterised using reverse-phase high-performance liquid chromatography (RP-HPLC), electrospray ionisation mass spectrometry (ESI-MS), Fourier-transform infrared spectroscopy (FTIR), and nuclear magnetic resonance (NMR) spectroscopy
