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Description
Additional evidence for a protective role of GPx1 can be in many other disease models, including stroke [106109], and neurodegeneration caused by trauma [114, 115], neurotoxins [116], and AD [123, 124]

Taslimi P, Aslan HE, Demir Y, Oztaskin N, Mara A, et al

doi: 10.1016/j.pmpp.2015.09.001 68 HollandD.Ben-HayyimG.FaltinZ.CamoinL.StrosbergA

Chapter 10

Alcohol depletes glutathione: Chronic alcohol consumption severely reduces hepatic glutathione through increased oxidative stress during ethanol metabolism [6][35]

Recently it was reported that the protein C9orf72, a guanine nucleotide exchange factor (GEF) [37], interacts with the Rab1/ULK1 complex, allowing its recruitment to the phagophore and mediating the initial step of autophagy
