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Slices were co-labelled with Myelin Basic Protein (MBP) [1:100, MAB386] and Myelin Oligodendrocyte Glycoprotein (MOG) [1:250, ab233549] ( n = 3 slices per timepoint and treatment)

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Copper can also oxidize Tau, forming intramolecular disulfide bridges via binding to the C291 and C322 on the R2 and R3 sequences, promoting both Tau phosphorylation and aggregation and also being detected in NFTs (Zubi et al., 2020)

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