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Dietary l-carnitine supplementation modifies the lipopolysaccharide-induced acute phase reaction in dairy cows

CACT acetylation mechanism is in line with a dynamic post-translational protein control that could undergo an on/off switch induced by deacetylation/acetylation linked to the availability of acetyl-CoA 57

[DOI] [PubMed] [Google Scholar] 72.Deprince A, Haas JT, Staels B

Considering that the majority of available data come from animal studies with a daily dose of 20 mg/kg, using the calculation based on body surface area proposed by Nair and Jacob in 2016 [43], we can hypothesize that the human equivalent dose could be 1.6 mg/kg, or 112 mg per 70 kg for an adult

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Found naturally in the body, acetyl-l-carnitine supports the availability of acetyl-CoA, an important energy generating metabolite