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Similarly, GSH transporters to the mitochondria await discovery

In contrast to GSH synthesis, which occurs intracellularly, GSH degradation occurs exclusively in the extracellular space, and in particular, on the surface of cells that express the enzyme -glutamyl transpeptidase (also called -glutamyl transferase, GGT

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doi: 10.1371/journal.pone.0065475

Currently, data on NAC supplementation suggest that doses of 1.22.0 g/day, taken acutely or over several weeks, may affect performance outcomes, with minimal benefits [4]

In the United States, minor nutrient deficiencies are relatively uncommon