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Comprehensive toxicology evaluations reveal that the compound does not affect food intake, body temperature regulation, or basic physiological parameters at effective doses in animal models, indicating that its metabolic effects occur through specific pathway modulation rather than general physiological disruption

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[DOI] [PubMed] [Google Scholar] 101.Sorbara M.T., Dubin K., Littmann E.R., Moody T.U., Fontana E., Seok R., Leiner I.M., Taur Y., Peled J.U., van den Brink M.R.M., et al

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In: Seminars in immunology