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validation, R.D.R., D.M., S.F
Since the discovery of the first xCT inhibitor erastin [80], derivatives like imidazole ketone erastin (IKE) was developed to improve solubility meanwhile introducing lysine-reactive ketone as a covalent warhead, thereby achieving nanomolar IC 50 [81,82]

Genetic diagnosis in hereditary hemochromatosis: discovering and understanding the biological relevance of variants
Epidemiological investigations have demonstrated that quercetin can reduce the risk of T2DM (124127)
