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According to current AD hypotheses, tau becomes abnormally phosphorylated, dissociates from microtubules, and aggregates into NFTs (193)

Additionally, dietary micronutrients such as folate and vitamins B12 and B6 contribute to 1C metabolism, as shown in Figure 2

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A stress-induced dysfunction of the hypothalamus-pituitary-adrenal axis is found in patients with endometriosis with an attenuated cortisol response, a condition known as burnout