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While results are required to be submitted no later than 12 months after the Primary Completion Date, Collins notes for certain applicable clinical trials, the period is up to three years. If the drug or biologic was not approved, licensed, or cleared by the FDA, the results may not be due at all

Emerging strategies to increase the bioavailability and therapeutic efficacy of phytochemicals in cancer therapy Phytochemicals have high anticancer effects that are multi-targeted, regulating the activation of the PI3K/Akt, MAPK, and NF-kB signaling pathways, yet their use in the clinic is impacted by low aqueous solubility, chemical instability, low membrane permeability, and rapid metabolism [175, 309]

A Review of Shrimp Cellular Receptors for WSSV: Potential Targets for Antiviral Strategies in Shrimp Aquaculture

doi: 10.1016/j.immuni.2014.10.004, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] Cunningham M., Azcarate-Peril M

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