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ALS-associated mutant TDP-43 is known to be aberrantly localized in mitochondria, but suppressing its mitochondrial localization protects against neurotoxicity in TDP-43 A315T mice (Wang et al., 2016)

A free radical is any molecule capable of independent existence that contains an unpaired electron in an atomic orbital

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These effects are primarily attributed to catechins contained in green tea leaves, particularly epigallocatechin-3-gallate

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