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Two recent studies reported a synergistic effect when combining FLT3 inhibitors (AC220) and autophagy inhibitors (C43) [57] or (TAK165) [58] for effectively killing AML cells

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3.7.4 Phenolic acids demonstrate pathway-specific miRNA regulation Ferulic acid specifically targets the miR-221/TP53INP1 autophagy axis

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217,218 This effect is known as hormesis

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