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Vascular alterations, such as endothelial dysfunction, increased arterial stiffness, enhanced intima-media thickness, and arterial wall calcification, are prevalent even in young women with PCOS (9496)
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Sulforaphane inhibits TGF-beta-induced epithelial-mesenchymal transition of hepatocellular carcinoma cells via the reactive oxygen species-dependent pathway

Hence the recommendation is to take supplements with meals, as this is the optimal timeframe to metabolize histamine in the digestive tract, thus minimizing its absorption

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