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For example, cellular senescence, classified as an antagonistic/secondary hallmark of aging, results as a consequence of persistent DNA and/or proteomic damage (primary hallmarks) that drives integrative hallmarks such as chronic inflammation and altered intracellular signaling, which further perpetuate other aging hallmarks

[Google Scholar] 75.Narula N., Wong E.C.L., Dulai P.S., Marshall J.K., Jairath V., Reinisch W

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It was first registered by the United States Environmental Protection Agency (US EPA) in 1975 for weed control and classified as a group D carcinogen