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GHK-Cu (Glycyl-L-Histidyl-L-Lysine copper complex, also known as Copper Tripeptide-1) is a naturally occurring tripeptide bound to a copper ion (Cu)

378 Astrocytic overload with iron however significantly reduces glutamate clearance by down-regulation expression of EAAT1 glutamate transporters 379 and impairs operation of the glymphatic system

[] The increased metabolic rate during this catabolic phase leads to elevated glutamine utilization

Androgen deprivation therapy (ADT), the first line of treatment for progressive prostate cancer, is effective at first but eventually fails due to the development of resistance, primarily through androgen-independent reactivation of AR [2]

This emphasizes the need for trace element balance for thyroid health and illness prevention [93]

However, it remains unclear how ferroptosis regulates immune cell infiltration in the tumor microenvironment of kidney cancer and how it promotes the transition of M2 macrophages to M1 macrophages