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Fifth, differences in patient characteristics, such as sex, were observed in the RCTs with provided IPD, which increased heterogeneity across studies

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Chronic liver diseases (CLDs), including viral hepatitis, alcohol-related liver disease (ALD), metabolic dysfunction-associated steatotic liver disease (MASLD), autoimmune liver diseases, cirrhosis, and liver cancer, pose a major threat to global public health 2,3,4

Reduce the dose temporarily and re-attempt the increase later

For Medicare beneficiaries, an Advance Beneficiary Notice (ABN) is required

To expand beyond cysteine modifications, Chen and colleagues developed a reaction that utilizes lysine and arginine residues for cyclization