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Vitamin C protects retinal ganglion cells via Spp1 in Glaucoma and after optic nerve damage

Nature 407 , 249257 (2000)

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Meanwhile, their experiments also indicated that the levels of ferroptosis-associated biomarkers such as iron content and toxic lipid peroxides were increased in transforming growth factor beta1 (TGF-1)-stimulated NRK-52E cells and type 1 diabetic mice[83]

Building on this foundation, we highlight representative studies that integrate RT with cGAS-STING pathway activation, focusing on three key aspects: (1) enhancing tumor and immune cell responses, (2) remodeling the TME, and (3) multimodal therapies combining RT, STING agonists, and other therapeutic strategies