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Without ongoing MC1R stimulation, pigmentation returns to baseline within 6090 days

Cardiovascular Diabetology, 23 , 245

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Being a mild keratolytic agent and strong moisturizer means that high-percentage (10-40%) urea treatments are found effective in a bunch of skin disorders connected to excessive dryness and malfunctioning skin barrier such as ichthyosis, xerosis, psoriasis, eczema and seborrheic dermatitis

Carnitine is the transport system used by long chain fatty acids inside the cells

Note that the fatty acid components (R & R') may be saturated or unsaturated