first large study of glp 1 receptor agonists during pregnancy Discontinuing GLP-1s before or early raises risk for complications Use of GLP1 receptor agonists
Description
Born in Uddingston, Lanarkshire, a coal mining district of Scotland, Black's father was colliery manager who had started work in the pits at the age of 13 and his mother was a seamstress

Derek Thompson: How long did it take Lilly to recognize that what had begun as a type 2 diabetes drug was in fact an incredibly powerful weight-loss drug

Glucagon-like peptide-1 and its class BG proteincoupled receptors: a long march to therapeutic successes
[DOI] [PMC free article] [PubMed] [Google Scholar] 172.Pan W., et al

ArmstrongMJGauntPAithalGPBartonDHullDParkerRet al
These studies (called the STEP Trials) found that Wegovy led to significantly more weight loss (16% weight change) over 68 weeks compared to people taking a placebo drug (5.7% weight change)
