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Int J Mol Sci (2021) 22(15):8309

However, even people with a standard level of B12 can benefit from B12 shots on a regular or one off basis, because there a wide range of health advantages associated with this one vitamin

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10.2174/13816128113199990421 62 SeiwerthS.MilavicM.VukojevicJ.GojkovicS.KrezicI.VuleticL

each case is judged individually.11 Solid evidence on the safety of parenteral, lifelong, high dose hydroxocobalamin is available from decades of treating patients with inborn errors of B 12 metabolism (eg, cobalamin C deficiency).6768 Symptom monitoring Monitor symptoms regularly (eg, every two to three months) as they may reappear, even after several months, if injection frequency is reduced