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In the case of X203, it is designed to block another natural protein with potent effects on aging: interleukin 11, whose concentration increases with age, causing cells to stop multiplying while accumulating and releasing harmful substances that cause inflammation and damage to nearby cells

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Importantly, functional B12 deficiency can sometimes coexist with high total B12 levels, especially in kidney disease, and may require additional testing with methylmalonic acid (MMA) or holotranscobalamin if deficiency is suspected clinically

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Ensure the pharmacy is in-network with the patients plan or inform patients they may need to seek reimbursement if out-of-network