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With obesity now recognized as a global health crisis affecting both developed and developing countries, healthcare systems and pharmaceutical companies are under pressure to find new, safe, and effective therapies

Why Combination Therapy Matters Obesity is a multifactorial disease requiring multi-pathway intervention

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In addition, multiple food intolerances commonly develop as the situation goes untreated

Researches have shown a positive correlation between chemotherapeutic resistance and the number of spontaneous genetic mutations [130]

Upon HGF binding c-MET gets activated through kinase activity which is followed by receptor dimerization and trans-phosphorylation of two catalytic tyrosine residues Tyr1234 and Tyr1235 within the kinase activation region [31]