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Evidence suggests it may promote weight loss by increasing calorie expenditure

Mechanistically, high expression of BCAT1 reduces the NAD + /NADH ratio, increases mTORC1 activity, and promotes oxidative phosphorylation and nucleotide biosynthesis

Additionally, although rare, there have been reports linking green tea extract supplementation to liver-related issues, particularly in individuals with sensitive metabolisms or those taking high doses for extended periods (Saha et al., 2024)

In addition, 24 h before the experiment, 200 L of Seahorse Bioscience Calibrant media (pH 7.4) was added to each well of the utility 96-well plate to hydrate the XFe96 sensor cartridge

AMPK is a recipient of metabolic signals in peripheral tissues but also functions as an upstream modulator of hormonal pathways by regulating their neural secretions

Carnitine flux studies To determine intracellular acylcarnitines, primary WT and CD37KO splenocytes were isolated as described above, washed with PBS and stored at 80 C until further processing