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10.1186/s12929-018-0438-0 212 Yamada-FukunagaT.YamadaM.HamataniT.ChikazawaN.OgawaS.AkutsuH.et al (2013)

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Despite its efficacy, particularly in younger animals, ASTs neuroprotective effects appear to diminish with age, highlighting the need for further research to optimize its therapeutic potential

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This rescue operation potentially allows the immune system to reset, stopping the continuous, inappropriate inflammatory signaling that drives daily symptoms and supporting a more balanced, effective immune response