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In addition to the Leu198Leu genotype in the GPx1 gene, the Ala16Ala genotype in the manganese superoxide dismutase ( MnSOD ) gene, the most significant enzyme that protects against ROS in the human body [90], was also associated with an increased risk of breast cancer [91]

Glutathione is a tripeptide, meaning it is made of three amino acids: cysteine, glycine, and glutamic acid

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doi: 10.1074/jbc.M305569200

Defining these interactions is essential for elucidating molecular mechanisms, understanding disease pathways, and developing targeted therapeutics