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The medication is typically administered as a once-weekly subcutaneous injection

Semaglutide-treated rats show downregulation of many type IV and type VI collagens and laminin genes that compose the basement membrane, as well as the type I, type III, and type V collagens and fibrillins that compose the interstitial matrix ( Figure 4B )

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This creates a negative association with protein foods, making users even less likely to eat enough

When combined, these effects might be stronger, making activities like driving or operating machines unsafe
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