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The prophylactic administration of BB in the murine model of UC (BB post-UC) reduced histological damage and prevented the expression of IL-1 by 61.12%, IL-6 by 94.70%, and TNF- by 68.88%, increased the expression of INF- by 177.06%, IL-4 by 541.36% and IL-10 by 531.97%, concerning the control group that underwent UC induction (H 2 O post-UC) (Table 5)

This implies that fewer ROS producing PBMC were activated during the first hours pp , but arguing against an immune suppression at this time is the finding that the ability to produce ROS was maintained over time

54 Radicular nerve pain One double-blind RCT amongst 64 patients with lower extremity radicular nerve pain compared the use of different doses of oral ALC (1180 mg/d versus 600 mg/d) with respect to total symptom score and EMG