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Description
Reduction of NNMT activity in research models may lead to observable changes in nicotinamide metabolism, methyl group utilization, and downstream cell signaling
Journal of Endocrinology, 236(2), 63-78
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What makes NNMT a significant metabolic target
An imbalance between the two can create oxidative stress that opens the gateway for aging as well as diseases such as high blood pressure, various cancers, and Alzheimers disease, and alcoholic liver disease
Long-term deficiencies may result in severe complications, such as nerve damage or cognitive decline
