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Nonetheless, translation of sulfide-based therapy to clinical practice has been stymied due to the very low therapeutic index of sulfide and the incomplete understanding of endogenous sulfide metabolism

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Antioxidants are REQUIRED to prevent excess free radicals which lead to oxidative stress

10.1371/journal.pone.0160620 186 PasseriE.ElkhouryK.MorsinkM.BroersenK.LinderM.TamayolA.et al (2022)

In our simulations, non-methylated DNA (nDNA), center-methylated DNA (cDNA) and fully-methylated DNA (fDNA) were subjected to a stretching force directed along the helical axis

Lee J, Kim S (2018) Kidney-on-a-chip: a new technology for predicting drug efficacy, interactions, and drug-induced nephrotoxicity