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This article was researched between April and May 2026

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Neuropathy is believed to result from pyridoxine neurotoxicity to dorsal root ganglia when plasma levels are excessively high

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In fact, a 2008 study found that after taking a 1,000 mcg oral supplement, only approximately 1.3% (or 13 mcg) of B12 was absorbed into the bloodstream

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