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Bronchial smooth muscle remodeling involves calcium-dependent enhanced mitochondrial biogenesis in asthma

However, the hydrophobic pocket formed by the three aromatic residues has been suggested to shield the catalytic nucleophile from bulk solvent and activating hydrolysis

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Antibiotics, 11 (12), Article 1822
A Change.org petition on that very subject recently garnered more than 100,000 signatures, reflecting the groundswell of support for the motion
