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Therefore, the observed promotion of HaCaT migration and inhibition of fibroblast migration by P407 and the formulation is likely related to cell-type-specific signaling and their functional differences in skin repair processes 34

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These effects depend on integrin 1 and 1 pathway activation, creating functional outcomes of: Enhanced endothelial cell proliferation Increased cell migration to injury sites Improved tubule formation for angiogenesis No cytotoxic effects across wide concentration ranges Hair Follicle Stem Cells Hair follicle stem cells undergo amplification, demonstrated by follicle enlargement in mice

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