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Description
In general, histone modifications are associated with changes in stress-induced gene regulation (Guo et al., 2017), and the members of HDA subfamily share sequence homology in the HDAC domain and require the Zn 2+ cofactor for deacetylase activity (Yang and Seto, 2007
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[DOI] [PMC free article] [PubMed] [Google Scholar] 256.Hama S., Mizuno S., Kihara M., Tanaka T., Ogino C., Noda H., Kondo A
In clinical trials, participants lost an average of 15% to over 20% of their body weightnumbers previously seen only with bariatric surgery
Existing data come exclusively from preclinical (animal) literature
Comparison of calling pipelines for whole genome sequencing: an empirical study demonstrating the importance of mapping and alignment
