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The phenomenon of oxidative stress causes the occurrence of membrane depolarization phenomenon, i.e., the decrease in the difference of electric potential between the cytosol and the culture environment

Anthracyclines such as doxorubicin and epirubicin cause cell death and cytotoxicity by intercalating into DNA and disrupting replication, this is part of standard treatment (67, 215)

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Figure 5 Finally, the MR-PRESSO test detected 3 other outlier SNPs of PD on albumin (2 SNPs) and total bilirubin (1 SNP), 2 outlier SNPs of AD on total bilirubin, and 1 outlier SNP of ALS on total bilirubin, and this associations significance and magnitude did not change after removing the outliers