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Despite the concerns and limitations noted, there is no doubt that NQO1 has evoked great interest encompassing the areas of tumor biology, drug discovery, chemistry, and cancer imaging and has emerged as a tumor-selective drug target

[DOI] [PMC free article] [PubMed] [Google Scholar] 423.Dodson M., Shakya A., Anandhan A., Chen J., Garcia J.G.N., Zhang D.D

Qi XL, Xiu J, Shan KR, Xiao Y, Gu R, Liu RY, Guan ZZ

10.1378/chest.127.1.266 101
The Wolverine Protocol: Investigating the high-velocity signaling of VEGF and actin-binding proteins in soft tissue models

This binding modes also display important contacts in the Hydrophobic cleft, the spermidine and Z subsites (see Table 4)
