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Importantly, the increase in pharmacological efficacy after ibuprofen prodrug dosing could be explained by higher drug delivery of ibuprofen to the brain in prodrug form compared to the parent drug itself (145)

doi: 10.3389/fendo.2021.670031 65 ChenWFuJChenYLiYNingLHuangDet al

doi: 10.1002/biot.201500404

Unlike classical growth factors, BPC-157 exhibits a high degree of stability in gastric juice and oral bioavailability in animal studies, suggesting potential for systemic therapeutic effects

PLoS One 2012;7(12):e52572

Molecular pharmacology
