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G.ParamaswaranY.AliN.WaseemM.ShazlyG

PDZ1 binds the C-terminus of claudins (106) while the GUK domain interacts with occludin (107)
Following parenteral administration, aminoglycosides are eliminated unchanged in the urine by glomerular filtration
Mechanistic studies indicate that exercise-induced muscle contraction promotes the release of myokines (e.g., IL-6), which inhibit nuclear translocation of NF-B in hepatic Kupffer cells (Figure 2) (Milkovic et al., 2023)

doi: 10.1016/j.jconrel.2024.03.040 149 LiuZLiuKShiSChenXGuXWangWet al

Questions to Ask Your Doctor Curated prompts to bring to your next appointment
